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If you ask thirty of your friends that invest in the stock market what their average returns have been for the last decade, chances are

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

that their returns are all within a same range of returns give or take 5%. However perhaps one will stand out of the crowd, averaging 15

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

%, 20% or even 25% annual returns. And chances are that this one person that has drastically outperformed everyone else is doing somethi

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ng drastically different than all the others.

This simple exercise alone should tell you something. Find out what every other investor

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

is doing out there and do the opposite or do something different. Don’t just do the same thing that they are doing, because it wil

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

l lead you on the road to nowhere. Just as I stated in a previous blog (link) that most people are so lazy that they want someone else

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

to even tell them what to think, most investors are the same way. They’re unwilling to put in the time to learn how to make steady

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

, phenomenal returns, so they let someone else do their thinking for them – mostly large global investment firms. But think about

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

this. If the large global investment firms were doing the best thing for these clients, then most of these clients would state that thei

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

r portfolios return phenomenal returns every year. The fact that they don’t indicates that most likely you should be doing somethi

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ng very different from how the major investment firms manage your stock portfolio.

To me, contrarian investing isn’t just about b

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

uying stocks when people are selling and selling stocks that people are buying. To me, this isn’t contrarian investing at all. To

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

me, contrarian investing is about identifying opportunities that 99% of other investors haven’t. By definition, to build substanti

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

al wealth from investments you have to get in at the bottom of the market and sell at its height. That means you have to identify opport

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

unities before anyone else does, and buy assets that make people say “you bought what?” because they never considered buying

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

them.

In a previous entry, I discussed fast food and the fact that most people are not even aware of what’s in the food that the

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

y are eating. If you’re wondering what makes McDonalds fries taste so good, it’s the beef flavoring they use. Out of deferen

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ce to outraged Indian Hindus that believed that potatoes were actually a vegetarian product and to whom cows are a sacred animal, McDona

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

lds has stopped using beef flavoring in their French fries in the Indian market. By digging down the rabbit hole of the food industry yo

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

u discover interesting things about the foods you consume. And digging down the rabbit hole of investing is the ONLY way to build wealth

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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The 80 - 20 Principle asserts that a minority of efforts usually leads to a majority of the rewards. For example, 80 percent of what you achieve in your job comes from 20 percent of the time spent. For all practical purposes then, four-fifths of the effort - a dominant part of i - is largely irrelevant. This is contrary to what people normally expect.

Many Students have no credit rating and having a Credit Card is one way to build that credit rating. Many of them have special promotions for college students and more.

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