Useful Articles - Relationships

So you’ve just gone through a devastating break-up. My heart goes out to you. There is nothing quite as painful

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

as being dumped by someone you thought was the One. I know you’re probably feeling like your heart has been ripp

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

d out and stomped on and that your hopes and dreams have been shattered. Do what you have to do (within reason,

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

f course) to grieve this loss—cry, get angry, punch your pillow, throw darts at your ex’s picture.

One thing yo

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

u should not do, however, is visit, phone, email, or text you ex. You should have no contact whatsoever. Accept

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

he fact that it is over and make a clean break. Keep your dignity intact. Trust me on this—in the long run you’l

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

be glad you did.

Thoughts of revenge may be going though your head, but please, don’t act on them. Don’t sprea

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

d rumours, don’t betray old secrets, and don’t date or make out with his/her best friend to get even. Never reso

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

t to behaviour that you will regret in the future. Always act with class and remember that the best revenge is f

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

r your ex to see that you are doing just fine without him/her. You’ve moved on and are happy.

Keep in mind that

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

just because someone has broken up with you, it doesn't mean he or she no longer cares about you—it just means h

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

e/she no longer wants a relationship with you. It’s very likely that breaking up with you was just as hard on hi

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

/her as it was on you. If you take revenge, any affection that this person feels for you could turn into hatred,

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

and any chance you may have to re-establish a relationship (even if it’s just as friends) will be shattered.

Ha

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ve a pity party if you must, but do it in private. Then get off the couch, wipe those tears, and move on. It’s w

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

se to hold off on romantic relationships for a while. Give yourself some time to heal from this relationship. Wo

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

k on rebuilding your life and rekindling old friendships you might have neglected when you were in the relations

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

hip.

You may not realize it yet, but a new life has just opened up for you. While right now your break-up may s

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

em negative, it really was all for the best. You have just been given another chance to find your Mr. or Ms. Rig

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

t.

Al the best,

Joanne B. Parrotta

Author of A Matter of Destiny

Settling for second best is never an option

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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