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Useful Articles - Silk - Silk Production
If you're wondering where most of your silk comes from and the specialties of these countries, we're going to go inside the silk industry itself in
According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
Thailand, Japan, and China to see just what it is that they're making and how.
Silk production in Thailand is very specialized. The Thai silk mo
Silk production in Thailand is very specialized. The Thai silk mo
; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.
Examples of combination products may in
Examples of combination products may in
th is most suited to tropical conditions. This moth is what is called polyvoltine, meaning it can produce at least ten batches of eggs each year.
lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.
They hand reel the silk from the Thai moth from green cocoons. These cocoons still contain the live pupae. The pupae from these cocoons are not
here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
illed before being reeled because that would make reeling very difficult. What they do is they place the green cocoons in hot, almost boiling wate
d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.
Combination pro
Combination pro
r. This process loosens the end of the thread. They only have about 10 days to finish this process before the moths come out and ruins the cocoon
ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
. Many times, the workers run out of time. This limits the scale of the industry and partially explains why silk is so expensive. The most exper
easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
ence workers usually only produce about 300 kg per day.
Silk production in China and Japan is a little different. The moth that is mostly used in
Silk production in China and Japan is a little different. The moth that is mostly used in
nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
these countries is monovoltine or bivoltine. These moths produce one or sometimes two batches of eggs each year. These are then put into a suspe
and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
nded environment so that they can induce hatching at a more convenient time. These cocoons are very large so they are better suited for machine re
ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
ling. They produce a filament that is usually between one and two kilometers long. The adult moths that are normally used for production are too
ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.
Following aspects would a
Following aspects would a
fat to fly. The moths that can fly don't produce enough silk to be worth cultivating.
The larvae farmed by the silk makers of China and Japan, un
The larvae farmed by the silk makers of China and Japan, un
dd to the challenges in developing combination products:
Which markets to tap where the combination products can do fairly well?
Which combination prod
Which markets to tap where the combination products can do fairly well?
Which combination prod
like the ones in Thailand that are very sturdy, are very fragile and need great care. They are selectively bred and their purpose is strictly to g
cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
et maximum output with a minimum amount of work. In Thailand they get about 26 kg of raw silk per hectare. The production in Korea is about 80 kg
tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
per hectare and in China it is 125 kg per hectare.
In 1995 a major silk producing factory was set up in Hanzhou, China. This factory has the capa
In 1995 a major silk producing factory was set up in Hanzhou, China. This factory has the capa
t?
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
city to make over one million silk blouses every year. Yes, silk production in these countries is big business and makes up a large part of their
ping new procedures for reviewing their safety, efficacy and quality.
Professional from academic institutions, pharmaceutical industries, health care indust
Professional from academic institutions, pharmaceutical industries, health care indust
economy.
While silk production in these countries may be big business, there are those who, because of the nature of the industry, would just as s
While silk production in these countries may be big business, there are those who, because of the nature of the industry, would just as s
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
on see it die a quick death. The reason is simple. In the making of these silk products, living creatures die. While this isn't anything new (ju
.
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
st take a look at the fur coat industry) the activists against this industry are probably one of the most vocal, staging rallies and marching in pr
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.
Companies that provide selfless information through particip
Companies that provide selfless information through particip
otests. So far, however, their efforts have not even slowed down one of the largest industries in that part of the world. But the fight continues
tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products
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