Useful Articles - Health and Fitness

If you have undergone a teeth-whitening procedure, it shows that you place great care on your personal appearanc

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

e. And if you've gone to all the trouble of having your teeth whitened, you obviously wouldn't want to lose all

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

hat whiteness again. You would take all the necessary steps to maintain the whiteness of your teeth. After all,

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

teeth whitening procedure is a long-term investment that should be maintained. Otherwise, you'd have to invest

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ime and money once more to get your teeth white again.

So how exactly can you maintain your teeth after unde

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

going a teeth-whitening procedure?

* Rinse your mouth or brush your teeth each and every time you finish ta

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ing your meals. Use anti-bacterial mouthwash or toothpaste that has whitening properties. The quickest way to lo

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

e the whiteness of your teeth is to leave them stained and discolored by the foods you eat. The longer these foo

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

s stay in your mouth, the quicker they'll affect the color of your teeth.

* Use toothpaste that has teeth white

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ing properties. Use it regularly (after every meal) and you can be fairly certain that you'll have white teeth f

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

r a long period of time. A toothpaste with whitening properties protects the teeth from getting stained and disc

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

olored.

* If you are a heavy caffeine drinker (coffee, soda or tea) and simply cannot get rid of the habit, dri

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

k with a straw. The straw will protect your teeth from stain and discoloration because the caffeine will bypass

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

our teeth. Of course, if you can live without caffeine, this would be a much better way as not only will it keep

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

your teeth white, you'll be much healthier (and you'll sleep better).

* If at all possible, avoid using lipstic

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

as certain types of lipstick can stain your teeth and cause discoloration.

Treat teeth whitening as an investm

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

nt. You don't want to lose it by neglecting to take the necessary care towards maintaining your teeth. How often

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

do you think you can afford to take teeth whitening treatments again and again? Getting a teeth whitening proced

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

re done is akin to buying a new car and failing to maintain it on a regular basis. Unless you take an active rol

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

in taking care of your teeth, that teeth-whitening procedure is just going to be a waste of your time and money

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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