Useful Articles - Health and Fitness

I realize this sounds like a broken record, but if you want to loose weight and keep it off then you need weight loss exercise as part of your routine!

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

Whether you think “but I don't want to exercise, I hate exercise, I don't need to exercise”... or whatever other excuse you might have, the fact is we

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ght loss exercise is the key to success.

The bottom line is you can join whatever fad diet you want.. if you do not start a weight loss exercise routi

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ne then your chances of successful weight loss will be dropped dramatically. Sure you will loose some weight, after all that is achieved simply by cons

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ming less calories then your body requires to function. The problem is simply starving your body causes it to go into a fasting state. This is a defens

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ive move that your body takes to help you survive, what happens is your metabolism slows down which in turn gives you a felling a fatigue plus it tries

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

to store up extra fat reserves.

This is why weight loss exercise is so important!

Now you might be thinking, will not my body do that even if I am wo

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

rking out?

Think about this for a second, say you consume 3000 calories a day and your body burns 2200 with your everyday activities, if you suddenly

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ut those calories to below 2200 and do not start any weight loss exercise program then your body simply resorts to a fasting state and tries to protect

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

your body from starvation. Now you will loose fat, however your body will also loose muscle as it tries to fill in those calories that you are not tak

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ng in… and worse of all you will feel hungry, lethargic and miserable. Your mouth will be drooling for food and you will feel like crap

Ok so what doe

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

s weight loss exercise have to do with this?

Exercise causes your body to burn calories; it also increases your energy levels. So instead of starving

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ourself thin, keep eating the same amount of calories you are currently eating and instead increase your calorie burning to overtake your consuming. No

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

w that might sound hypocritical because would you not still be starving yourself. Simply no… your muscles will be getting worked, your heart will be pu

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ping and your body will become an efficient calorie burning machine. Once you start exercising you will find that you will want to start eating healthi

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

er and you will start eating foods that are not empty calories… that is foods with high calories and fill the gap for only short periods of time.

Howe

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

er, this is not a completely true statement… the reason is because everyone is different. So if you start an exercise routine and still feel you are ra

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

venous for junk food, then intervention is needed. For some this could be as simple as taking a fiber supplement that expands and fills the gap others

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ight try different appetite suppressants that fool the body into not feeling hungry. The point is, start a weight loss exercise program and listen to y

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

our body. If supplements are needed in conjunction with a weight loss exercise routine, then try them, but please don't try just starving yourself thin

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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